A decade after the Institute of Medicine report, “To Err is Human, Building a Safer Health System,” preventable and sometimes fatal patient incidents continue to plague healthcare. Even with significant worker training and the increased use of technology, medical errors and avoidable adverse incidents involving hospitalized patients continue to occur. To address this, numerous strategies have been developed and implemented, and one, in particular, seems to be gaining in popularity. This is the use of checklists, long a staple in the broad field of safety management and especially advocated by “high reliability organizations,” such as aviation and the nuclear industry. Despite that, their use had not really taken hold in healthcare until patient safety experts started to envision healthcare as a “high reliability organization.” In this paper, I address a new strategy to deliver better results with two recently developed safety checklists.